Relationship of Catalysis and Active Site Loop Dynamics in the (βα)8-Barrel Enzyme Indole-3-glycerol Phosphate Synthase
S Schlee, T Klein, M Schumacher, J Nazet, R Merkl… - Biochemistry, 2018 - ACS Publications
… The (βα) 8 or TIM barrel is the most common single-domain enzyme fold in … enzyme, namely
indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus (…
indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus (…
A conserved folding nucleus sculpts the free energy landscape of bacterial and archaeal orthologs from a divergent TIM barrel family
R Jain, K Muneeruddin, J Anderson… - Proceedings of the …, 2021 - National Acad Sciences
… indole-3-glycerol phosphate synthase (IGPS) TIM barrel … for three thermophilic indole-3-glycerolphosphate
synthase (… correlations between the archaeal Sulfolobus solfataricus (SsIGPS) …
synthase (… correlations between the archaeal Sulfolobus solfataricus (SsIGPS) …
[HTML][HTML] Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints
YH Chan, SV Venev, KB Zeldovich… - Nature …, 2017 - nature.com
… a model TIM barrel protein, indole-3-glycerol phosphate synthase (… TIM barrel fold proteins,
indole-3-glycerol phosphate … Thermophilic proteins employ multiple mechanisms to maintain …
indole-3-glycerol phosphate … Thermophilic proteins employ multiple mechanisms to maintain …
The complex role of sequence and structure in the stability and function of the TIM barrel proteins
YH Chan - 2017 - repository.escholarship.umassmed …
… a model TIM barrel protein, indole-3-glycerol phosphate synthase (… synthase (IGPS) from
Sulfolobus solfataricus, show different … TIM barrel fold proteins, indole-3-glycerol phosphate …
Sulfolobus solfataricus, show different … TIM barrel fold proteins, indole-3-glycerol phosphate …
Loop dynamics and the evolution of enzyme activity
… of TIM-barrel fold enzymes … indole-3-glycerol phosphate synthase (IGPS or TrpC in Fig.
2, centre right), which catalyses the closure of the CdRP ring into indole-3-glycerol phosphate (…
2, centre right), which catalyses the closure of the CdRP ring into indole-3-glycerol phosphate (…
Functional Distribution of Archaeal Chaperonins
L Gao, S Fujiwara - … Chaperonins: Multiple Copies and Multitude Functions, 2017 - Springer
… that the beta subunit is more stable than the alpha subunit. … the sequence from a thermophile
increased thermostability and … CpkA substrate, indole-3-glycerol-phosphate synthase (TrpC …
increased thermostability and … CpkA substrate, indole-3-glycerol-phosphate synthase (TrpC …
Anthranilic Acid–Tryptophan Alkaloids
ZY Tang - From Biosynthesis to Total Synthesis: Strategies and …, 2016 - Wiley Online Library
… forms indole‐3‐glycerol phosphate (InGP) by InGP synthase. … tPRAI has a TIM barrel fold,
whereas helix alpha5 in ePRAI is … synthase from the hyper thermophilic archaeon Sulfolobus …
whereas helix alpha5 in ePRAI is … synthase from the hyper thermophilic archaeon Sulfolobus …